أَسْتَوْدِعُ اللَّهَ دِينَكَ وَأَمَانَتَكَ وَخَوَاتِيمَ عَمَلِكَ
Astawdi'ullaha dinaka wa amanataka wa khawatima 'amalik
I entrust to Allah your religion, your trusts, and the conclusions of your deeds.
The Prophet ﷺ would say this when seeing someone off on a journey. Three things entrusted: your deen (religion — travel can weaken religious practice), your amanah (trusts — responsibilities to family and others), and your khawatim (endings of deeds — the last deed determines your outcome). It is a farewell that covers both worlds — your worldly responsibilities and your spiritual safety.
Related Du'as
اللَّهُمَّ بَارِكْ لَهُمْ فِيمَا رَزَقْتَهُمْ وَاغْفِرْ لَهُمْ وَارْحَمْهُمْ
O Allah, bless them in what You have provided for them, forgive them, and have mercy on them.
Sahihاللَّهُمَّ إِنَّا نَسْأَلُكَ فِي سَفَرِنَا هَذَا الْبِرَّ وَالتَّقْوَى وَمِنَ الْعَمَلِ مَا تَرْضَى
O Allah, we ask You in this journey of ours for righteousness and piety, and for deeds that are pleasing to You.
Sahihاللَّهُمَّ هَوِّنْ عَلَيْنَا سَفَرَنَا هَذَا وَاطْوِ عَنَّا بُعْدَهُ
O Allah, make this journey easy for us, and fold up its distance for us.
Sahihاللَّهُمَّ إِنِّي أَعُوذُ بِكَ مِنْ وَعْثَاءِ السَّفَرِ وَكَآبَةِ الْمَنْظَرِ وَسُوءِ الْمُنْقَلَبِ فِي الْمَالِ وَالْأَهْلِ
O Allah, I seek refuge in You from the hardships of travel, depressing sights, and a bad return regarding wealth and family.
Sahih